In this article
What is Clonidine
Clonidine high, or its other names: Clonidine, Clophelin, Katalpressan, Hemiton, Attensin, Capresin, Clonidone, Hyposin, Kapvay is an antihypertensive agent that acts at the level of neurohumoral regulation of vascular tone and is used to treat hypertension, glaucoma, and migraine. In this article you can find out Clonidine side effects, what precautions should be done before taking and other useful information. Clonidine classification is the following: Clonidine drug class is centrally acting alpha-agonist hypotensive agents. At first, it was used as a drop in a runny nose, thanks to the spasmodic action. But very quickly they noticed the ability of it to reduce blood pressure, and then Clonidine uses changed. It became a hypotensive and sedatives meds for anxiety.
What is Clonidine used for?
The treatment of hypertension, hypertensive crises and withdrawal syndrome in drug addicts – all this is what is Clonidine used for. The administration of Clonidine is not limited to oral. It can also be taken parenterally, sublingually, and in the form of instillation into the eye. In ophthalmology, the drug is used in the treatment of primary open-angle glaucoma, which is caused by moderately high or high intraocular pressure. As drops, it reduces the production of intraocular fluid and improves its outflow. The use of clonidine leads to a decrease in heart rate, systolic and diastolic blood pressure. Sometimes, doctors prescribe this Clonidine for sleep for ADHD. Clonidine HCl should not be prescribed at the same time as antidepressants and antipsychotics in high doses.
As a therapeutic treatment, it is applied for ADHD together with psychostimulants, reducing their side effects. It is used as an additional agent for epidural anesthesia, as well as removes strong pains in patients with cancer when opiate agents are not sufficient. The result of the general effect of Clonidine on the central nervous system can be called these: anesthetizing, sedative, sleeping pills and lowering the temperature.
Clonidine mechanism of action
It has a number of undoubted advantages, among which one can note the low cost, high efficiency, and availability in pharmacies. Because of the complex chemical processes, the active substance penetrates through the intercellular membranes into the medulla oblongata, which acts on the hypotensive, sedative and analgesic effects. Tranquilizers and anesthetics may probably increase the effect of Clonidine, although there is still no reliable clinical data on such interactions.
Clonidine side effects
The most severe Clonidine withdrawals are the cardiogenic shock, arterial hypotension, sinus node weakness syndrome, pronounced cerebral vascular changes, and depression. In the early days, there is also a sedative effect, increased fatigability, drowsiness, dizziness. Excess of recommended doses can lead to orthostatic hypotension, collapse, cardiac arrhythmias (especially in patients with pathology of the conducting system of the heart). In some cases, when using Clonidine in high doses, gynecomastia, depression, pain in the parotid gland and the appearance of scarce discharge from the nose are possible.
By Сlonidine overdose are implied in drowsiness, symptomatic hypotension, orthostatic reactions, bradycardia, periodic vomiting.
During the period of use, it is necessary to refrain from alcoholic beverages, driving, as well as occupations that require clarity of reactions and increased concentration of attention.
As a hypotensive agent, it is usually prescribed in the initial dose of 0.075 mg 2-3 times a day. In the manifestations of cerebrovascular arteriosclerosis, clonidine is administered at an initial dose of Clonidine 0.1 mg. In parenteral intake of clonidine, the patient should be in the lying position and then continue to remain immobile for another 2 hours.
When treating with Clonidine, it is important to monitor blood pressure regularly. Drinking alcohol is prohibited during treatment. When performing various types of operator activities, it should be taken into account that clonidine reduces the speed of psychic and physical reactions. The abrupt cancellation of Clonidine can lead to the development of a withdrawal syndrome (hypertonic crisis, irritability, tremor, headache, nausea), therefore, it is necessary to gradually reduce the dose before it is canceled for 7-10 days. In the development of the withdrawal syndrome , immediately return to the administration of clonidine, and in the future it is canceled gradually, replacing other means. To prevent the withdrawal syndrome, clonidine should not be prescribed to patients who do not have the conditions for their regular intake.
How to buy and where to buy
Keep in mind that although it is not the opiate class, it cannot be used without medical need and prescription. Clonidine and alcohol are impossible to mix to avoid harsh Clonidine side effects
Clonidine can be bought from registered online pharmaceutical stores such as ADV CARE, online pharmacy, Chemist Warehouse or online stores such as Amazon, eBay.