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Piracetam is a neurotransmitter, prototype for racetam group of synthetic supplements aimed to ensure cognitive intensification. It is a nootropic supplement and a derivative of the neurotransmitter gamma-aminobutyric acid (GABA) worked by restoration of cell membrane fluidity. Primarily marketed as a nootropic or one of the brain boosters, it is sold under various brand names with the most beloved ones being Nootropil, Qropi, Lucetam, and Dinagen. Notwithstanding that the med treats a huge variety of conditions such as vertigo, memory dysfunction, alcoholism, dyslexia, deep vein thrombosis, sickle cell anemia, oftentimes it is prescribed for curing myoclonic seizures.
Piracetam Effects and Benefits
- Vascular improvements – Piracetam reduces erythrocyte adhesion to vascular endothelium, impede vasospasm and alleviate cerebral and renal blood flow microcirculation. All of these reverberate the peripheral vasculature, as a result, it is showy against dyslexia, vertigo, sickle cell anemia.
- Cognitive Impairment – according to some reports, Piracetam was delineated as a drug that favors old people with mental degradation, dementia, amplify memory and other intellectual functions. The result surpassing to placebo in the treatment of adults with cognitive impairment. But its profitability
in such treatment is uncertain and overall the testimony is not consistent.
- Neural plasticity – it is reported that it has anticonvulsant and neuroprotective properties that are wholesome to the neural plasticity. For such reason, it is used in combo with other drugs to adults who suffer from myoclonic seizures in order to provide neuroprotective benefits.
- Aging-related conditions – preliminary evidence suggests Piracetam defends against neurological degradation over time. It is said to slow up the aging process and promote rehabilitation from alcoholism.
- Post-concussion syndrome – it has been found that for this syndrome low Piracetam dosage can improve blood flow to the brain which in turn may lead to the betterment of symptoms linked with this disorder. When it comes to preventing blood clotting after a cardiovascular lesion, Piracetam works as a useful supplemental interference.
How does it work
Interestingly, but Piracetam couldn’t be vended as a dietary supplement. This is a neurotransmitter without a fully examined mechanism of action. The drug has neuroprotective properties that are conceivably produced by its impact on the ion channels and carries on the neurons which, in turn, adduces to their irritability. Piracetam is lauded for the faculty of the brain to constitute new neural connexions and intensify its ability to indemnify for injuries. Cognitive improvement antecedents by magnification in the conversion of oxygen and glucose in the brain. However, mechanisms underlying the enhancement are not acknowledged.
The vascular effects, on the other hand, are brought about by drug’s action on the red blood cells, platelets, coagulation factors, and blood vessels. Piracetam improves the deformability of the membranes which leads to diminution blood toughness. It reduces platelet function without reducing their count. This, along with lessened levels of some coagulation factors, may result in amplified bleeding time. Furthermore, Piracetam also helps repress vasospasm but it lacks any actual vasodilatory outcome. It also induces the production of chemicals that salvage promotion healthy endothelium or blood vessel walls.
Piracetam issued in tablet, powder, and oral solution forms. Nootropil, the most popular trademark is available in 800mg and 1200mg film-coated tablets and 333.3mg/ml solution. The counseled maximum total dose is 24g per day separated into two to three doses. Onset at a weaker total daily dose of 7.2g then piecemeal increasing up to the maximum dose is advised. This medication can be taken regardless of the meal.
Piracetam dose is adjusted in individuals with compromised or impaired kidney function, and their creatinine clearance should be regularly monitored. For those with liver posers, no tuning is needed unless the individual writhes from kidney lesion.
If used with other anti-myoclonic drugs, the dose of these drugs can be lessened according to the clinical avail being obtained with Piracetam. The drug is illicit for individuals below 16 years old.
Once therapy with Piracetam is launched the consumption of the drug should keep on until disease persists. The dosage may be abated by 1.2g every two to four days to prevent relapse or withdrawal effect.
Piracetam Side Effects
It is well-tolerated by most patients and any unwelcome reactions are said to be temperate and interim. The most commonly reported adverse effects of the drug to arise at a dose of up to 1.6 to 15g per day. These include:
Less common Piracetam powder side effects are heightened libido, depression, hallucination, skin rash, somnolence, and weight gain.
Piracetam dangers are meager as the drug has an extremely low potential for acute toxicity. Overdose is possible only if substantial amounts of the drug is taken and may be expressed in abdominal pain, bloody diarrhea, nausea, and vomiting. To dispose of symptoms try to induction of emesis and gastric lavage. An antidote is nonexistent.
Piracetam powder precautions
There are few admonishments prevail for ones with kidney impairment, bleeding problems, gastrointestinal perturbation. The same goes for individuals who use blood-thinning medications or are going to incur operation (even dental surgery).
Early studies show that Piracetam can cross the placental barrier on pregnant women. So its use is authorized only in extreme necessity or when the benefits far override the risks. It is excreted in breast milk, so it is contravened for lactating women.
How and Where to Buy Piracetam
Despite the fact that it is legal and broadly used in Europe, Asia, and South America, Piracetam is not ratified for medical use in the United States. Now, it is granted to import the med for personal enjoyment.
The plainest solution is to buy Piracetam online, but read Piracetam reviews and consult your physician beforehand. The obtainable forms of the drug are Piracetam capsules, powder and tablets. Before making a decision, make sure that the supplier has a third-party certification. This will guarantee you a scatheless and secure product that you will get. Reckon procurement Piracetam Amazon, there a variety of reviews based on which you can make your choice.