Home Hormones What is high levels of serotonin: symptoms, causes and effects

What is high levels of serotonin: symptoms, causes and effects

Posted by admin in Hormones Category. Reviewed and Updated: 12 February, 2019
What is high levels of serotonin: symptoms, causes and effects

Ever puzzled about what regulates moods and sentiments in a human being? The hormone behind cheerfulness, positive emotions, and healthiness, a neurochemical that exists in CNS – is Serotonin. It occasionally even recognized as a happy hormone. Constantly, people experience melancholy and stress when the intensities of the hormone drop down.

To boot, Serotonin is involved in some functions in an individual’s body such as digestion of food and bone formation. Dopamine, a hormone in a human brain controls moods and responsible for nice feelings. High serotonin low dopamine causes depression. If you are wondered how to determine your level, let’s take a look.

What is serotonin?

What is serotonin?The hormone is sometimes referred by scientists as 5-HT due to the compound formula 5-hydroxytryptamine. Serotonin is naturally produced in the human body and it empowers different sensory system cells to speak across nerve cells. It is generated in the gut by a person’s intestines and in the brain, although it exists in blood platelets.

Shortage of serotonin signified in sadness, negative thoughts, feel tense and irritable, crave sweets, and low energy.

On the other hand, a too high level may lead to excessive nerve cell activity and cause dangerous symptoms. Here we will discuss what it means to have high Serotonin Level and how to live with such a condition.

High Serotonin Level called Serotonin condition – the ailment’s initial phase is suffused by shuddering and diarrhea whereas fever, paroxysm, and characterized tightness are alerts for a harsh serotonin condition. Medical attention is key, otherwise, it might cause death.

Excess serotonin might be because of several remedies which contain the medicine. If ingested the substances may possibly result in the hormone build up in one’s body. Moreover, the hormone bumps up because of accruing in a prescribed amount of a product or combining remedies that encompass serotonin like Effexor, Lexapro, and Zoloft. The symptoms start inside hours of taking another pharmaceutical med.

What does serotonin do?

What does serotonin do?The hormone’s effects are felt on almost every facet of a human’s body starting from gesticulation to emotions. The cheerful hormone is essential for the superior working of the duodenum tract, neurons, and nerves in an individual’s brain. It also synchronizes cognizance, learning, body hotness, and ravenousness. Besides the amazing advantages, a high serotonin level is hazardous. It could result in a situation that might cause death without a cure.

Indicator’s of High Serotonin levels

Subsequent to taking any medicine that contains Serotonin and raising the measured quantity or combining copious remedies that are serotonin-interrelated, an overdose of Serotonin might be experienced in a short period.

The indicators depend on the hormone intensities in an individual’s body but are quite unpleasant. Listed below are a number of high serotonin levels symptoms:

  • Indicator’s of High Serotonin levelsAnxiety, bewilderment, and irritability
  • Stiffness, and shudders
  • Ague
  • Agitation or eagerness
  • Queasiness and diarrhea
  • Speedy pulse rate and hypertension
  • Goose bumps and widened pupils
  • Uncontrolled thew movements and loss of muscle coordination
  • Muscle rigidity or jerking muscles
  • In extreme circumstances, the following are experienced;
  • Extremely high temperatures
  • Convulsions and uneven pulse rate
  • Coma or unconsciousness

Accompanying effects of high serotonin levels:

  • Sorrow, unresponsiveness
  • Lack of involvement
  • Jumbled attention
  • Trouble focusing and learning
  • Sluggishness and some bluntness
  • Nasal stuffiness
  • Unusual feeling of smell
  • Cold or flu-like feelings
  • Sleeping disorder
  • Sexual brokenness
  • Commotions in ears

Causes of High Serotonin

Causes of High SerotoninOptimally, the brain produces serotonin that is only bountiful for regulation of moods, inquisitiveness, conduct, and lowering temperature. However, the neurotransmitter portions rise when 2 or more prohibited products that contain serotonin are combined.

For instance, taking a certain pain reliever to manage a migraine and after consuming another antidepressant increases the hormone echelons. Nevertheless, consuming a single medicine that incorporates Serotonin cannot result in this disorder, except quite a few people are more vulnerable to any tablets with Serotonin.

A number of meds like antibiotics and antiviral prescribed to manage HIV/AIDS, opioid pain medications amplify the heights of serotonin. A few treatments that might intensify serotonin accumulation consist of:

  • Antidepressants – are the main reason for high serotonin levels and are amenable for treating hopelessness and franticness. But if misused the medicament could result in high serotonin levels anxiety. The substances function by escalating the intensities of Serotonin because of the remedy’s capability to occlude the hormone uptake by the brain’s nerve cells. People even take serotonin pills to control gloominess.

antidepressantsVarious antidepressants like SNDRIs (serotonin-norepinephrine-dopamine reuptake inhibitors) work by preventing serotonin uptake and several hormones along with stopping several neurotransmitters from being absorbed. Nevertheless, SSRIs produce a smaller amount of unsympathetic outcomes as compared to different antidepressants. Thus are occasionally called 2nd generation antidepressants. Some of the prescriptions are:

  • SSRIs like Viibryd, Paxil Celexa, and Prozac. Additionally, there are Effexor and Cymbalta.
  • Tricyclic substances like amitriptyline and nortriptyline
  • MAOIs like Nardil and Marplan
  • Migraine solutions – Anti-migraine solutions like carbamazepine (Targetol), triptans, and valproic acid are renowned to advance serotonin proportions in the brain.
  • Pain mitigating drugs – Twinge treatments universally opioids or narcotics such as hydrocodone and oxycodone, tramadol (Ultram) are associated with high serotonin levels.
  • Banned, illicit substances – Examples of prescriptions are amphetamines, cocaine and LSD
  • Vomiting treatments – The pills are Granisetron, Ondansetron, and Metoclopramide.
  • Cough treatments – Dextromethorphan is such an example.
  • Herbal substances – Nutmeg is amongst the herbal products influence the hormone level as well as St. John’s wort and ginseng
  • Diet – Although augmented altitudes of serotonin are principally caused by treatments, naturally high serotonin levels is because of varieties of foods. Serotonin does not exist in nourishment but in Tryptophan. Some foods high in Serotonin consist of nuts, eggs, and pullet.

Diagnosis and cure of Serotonin condition

Diagnosis and cure of Serotonin conditionThere exists no predetermined laboratory stratagem for diagnosing the situation. The health doctor evaluates the wellness testimony and the signs implicated.

Medical examinations like complete blood test incorporate – drug screening, kidney and liver working tests should be undertaken to eliminate any other complications.

Withdrawal from the drug which causes the rise of serotonin is the prime stage of treating serotonin condition. Treatments scuffle tenseness and spasms are prescribed. Cyproheptadine is given to prescribing serotonin emission. It can be swallowed or crushed to be taken by the use of a nasogastric tube.


Serotonin has superlative benefits. That is why it is a first-rate ingredient for many medications. However, combining such drugs increases serotonin proportions which result in serotonin ailment.

The ailment is a state pervaded by shivering, high temperatures, etc. The good thing is that it is curable. Do not fail to take painkillers out of trepidation of high serotonin levels, but do it consciously and moderation.

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